Sunday, June 21, 2015

#Diet #Health – New 5-Day ‘Fasting’ Diet Seems To Lower Disease Risk, Slow Aging – 

The new Fasting Mimicking Diet (FMD), developed by university researchers is under human trials in the United States. The new diet produces the best results when people starve by cutting calories for five days in a row. The “fasting” diet could help to produce results such as weight loss; better immune system; lower risk of cancer, heart disease and diabetes; and looking younger.

Researchers at the University of Southern California (USC) created the diet. They stated that most people would only stick to the diet plan four times every year. One of the benefits of the new diet is that there is no need for calorie reduction.  Significant lowering of caloric intake can result in people often feeling hungry and getting moody.

Dr. Valter Longo is a USC professor. He is also one of the main developers of the new fasting method.The findings of Longo’s recent study were published this week in the journal Cell Metabolism.

In the laboratory research, old mice were placed in cycles of a low-calorie diet for four days. The dieting effects included belly fat loss, more stem cells in many organs, and improved memory, according Tech Times. A human trial of FMD included 19 humans who completed a monthly “fast,” according to The Telegraph.  The fasting diet lasted 5 days.

New 5-Day ‘Fasting’ Diet Seems To Lower Disease Risk, Slow Aging

In 1850, the Reverend Thomas Kirkman, rector of the parish of Croft-with-Southworth in Lancashire, England, posed an innocent-looking puzzle in the Lady’s and Gentleman’s Diary, a recreational mathematics journal:

“Fifteen young ladies in a school walk out three abreast for seven days in succession: it is required to arrange them daily, so that no two shall walk twice abreast.” (By “abreast,” Kirkman meant “in a group,” so the girls are walking out in groups of three, and each pair of girls should be in the same group just once.)

Solve a variation of Thomas Kirkman’s puzzle by arranging nine girls in walking groups. And think fast—the clock is ticking. Emily Fuhrman for Quanta Magazine, with design by Olena Shmahalo. Collage resources from The Graphics Fairy and and Clker.

Pull out a pencil and paper, and you’ll quickly find that the problem is harder than it looks: After arranging the schoolgirls for the first two or three days, you’ll almost inevitably have painted yourself into a corner, and have to undo your work.

The puzzle tantalized readers with its simplicity, and in the years following its publication it went viral, in a slow, modestly Victorian sort of way. It generated solutions from amateurs (here’s one of seven solutions) and papers by distinguished mathematicians, and was even turned into a verse by “a lady,” that begins:

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About

Original story reprinted with permission fromQuanta Magazine, an editorially independent division of SimonsFoundation.org whose mission is to enhance public understanding of science by covering research developments and trends in mathematics and the physical and life sciences.

A governess of great renown,
Young ladies had fifteen,
Who promenaded near the town,
Along the meadows green.

While Kirkman later bemoaned the fact that his weightier mathematical contributions had been eclipsed by the popularity of this humble brainteaser, he was quick to defend his territory when another prominent mathematician, James Joseph Sylvester, claimed to have created the problem “which has since become so well-known, and fluttered so many a gentle bosom.”

The puzzle may seem like an amusing game (try a simpler version here), but its publication helped launch a field of mathematics called combinatorial design theory that now fills gigantic handbooks. What started as an assortment of conundrums about how to arrange people into groups—or “designs,” as these arrangements came to be called—has since found applications in experiment design, error-correcting codes, cryptography, tournament brackets and even the lottery.

Yet for more than 150 years after Kirkman circulated his schoolgirl problem, the most fundamental question in the field remained unanswered: Do such puzzles usually have solutions? Kirkman’s puzzle is a prototype for a more general problem: If you have n schoolgirls, can you create groups of size k such that each smaller set of size t appears in just one of the larger groups? Such an arrangement is called an (n, k, t) design. (Kirkman’s setup has the additional wrinkle that the groups must be sortable into “days.”)

Thomas Kirkman’s popular math puzzle was first published in the 1850 edition of the Lady’s and Gentleman’s Diary. Hathi Trust

It’s easy to see that not all choices of n, k and twill work. If you have six schoolgirls, for instance, you can’t make a collection of schoolgirl triples in which every possible pair appears exactly once: Each triple that included “Annabel” would contain two pairs involving her, but Annabel belongs to five pairs, and five is not divisible by two. Many combinations of n, k and t are instantly ruled out by these sorts of divisibility obstacles.

For the parameters that aren’t ruled out, there’s no royal road to finding designs. In many cases, mathematicians have found designs, through a combination of brute force and algebraic methods. But design theorists have also found examples of parameters, such as (43, 7, 2), that have no designs even though all the divisibility requirements check out. Are such cases the exception, mathematicians wondered, or the rule? “It was one of the most famous problems in combinatorics,” said Gil Kalai, a mathematician at the Hebrew University of Jerusalem. He recalls debating the question with a colleague a year and a half ago, and concluding that “we’ll never know the answer, because it’s clearly too hard.”

Just two weeks later, however, a young mathematician named Peter Keevash, of the University of Oxford, proved Kalai wrong. In January 2014, Keevash established that, apart from a few exceptions, designs will always exist if the divisibility requirements are satisfied. In asecond paper posted this April on the scientific preprint site arxiv.org, Keevash showed how to count the approximate number of designs for given parameters. This number grows exponentially—for example, there are more than 11 billion ways to arrange 19 schoolgirls into triples so that each pair appears once.

The result is “a bit of an earthquake as far as design theory is concerned,” said Timothy Gowers, a mathematician at the University of Cambridge. The method of the proof, which combines design theory with probability, is something no one expected to work, he said. “It’s a big surprise, what Keevash did.”

Winning Big

Mathematicians realized in the early days of design theory that the field was intimately connected with certain branches of algebra and geometry. For instance, geometric structures called “finite projective planes”—collections of points and lines analogous to those in paintings that use perspective—are really just designs in disguise. The smallest such geometry, a collection of seven points called the Fano plane , gives rise to a (7, 3, 2) design: Each line contains exactly three points, and each pair of points appears in exactly one line. Such connections gave mathematicians a geometric way to generate specific designs.

The geometric structure called a “Fano plane” corresponds to a (7, 3, 2) design. Gunther

In the 1920s, the renowned statistician Ronald Fisher showed how to use designs to set up agricultural experiments in which several types of plants had to be compared across different experimental conditions. Today, said Charles Colbourn, a computer scientist at Arizona State University in Tempe, “one of the main things [experiment-planning software] does is construct designs.”

Starting in the 1930s, designs also became widely used to create error-correcting codes, systems that communicate accurately even when information must be sent through noisy channels. Designs translate neatly into error-correcting codes, since they create sets (groups of schoolgirls) that are very different from each other—for instance, in the original schoolgirl problem, no two of the schoolgirl triples contain more than a single girl in common. If you use the schoolgirl groups as your “code words,” then if there’s a transmission error as you are sending one of the code words, you can still figure out which one was sent, since only one code word will be close to the garbled transmission. The Hamming code, one of the most famous early error-correcting codes, is essentially equivalent to the (7, 3, 2) Fano plane design, and another code related to designs was used to encode pictures of Mars that the Mariner 9 probe sent back to Earth in the early 1970s. “Some of the most beautiful codes are ones that are constructed from designs,” Colbourn said.

Design theory may even have been used by betting cartels that made millions of dollars off of Massachusetts’ poorly designed Cash WinFall lottery between 2005 and 2011. That lottery involved choosing six numbers out of 46 choices; tickets won a jackpot if they matched all six numbers, and smaller prizes if they matched five out of six numbers.

There are more than 9 million possible ways to pick six numbers out of 46, so buying tickets with every possible combination would cost far more than the game’s typical jackpot. A number of groups realized, however, that buying hundreds of thousands of tickets would enable them to turn a profit by scooping up many of the smaller prizes. Arguably the best assortment of tickets for such a strategy is a (46, 6, 5) design, which creates tickets of six numbers such that every set of five numbers appears exactly once, guaranteeing either the jackpot or every possible five-number prize.

No one has found a (46, 6, 5) design so far, Colbourn said, but designs exist that are close enough to be useful. Did any of the betting cartels use such a design “to siphon money from the Lottery at no risk to themselves?” wroteJordan Ellenberg, a mathematician at the University of Wisconsin, Madison, who discussed the Cash WinFall lottery in his book How Not to Be Wrong. If they didn’t, Ellenberg wrote, they probably should have.

It would be hard to make a complete list of the applications of designs, Colbourn said, because new ones are constantly being discovered. “I keep being surprised at how many quite different places designs arise, especially when you least expect them,” he said.

A Perfect Design

As the number of design applications exploded, mathematicians filled reference books with lists of designs that might someday prove useful. “We have tables that say ‘For this set of parameters, 300,000 designs are known,’” said Colbourn, a co-editor of the 1,016-page Handbook of Combinatorial Designs.

Peter Keevash of the University of Oxford. Peter Keevash

Despite the abundance of examples, however, mathematicians struggled to get a handle on just how often designs should exist. The only case they understood thoroughly was the one in which the smallest parameter, t, equals 2:Richard Wilson, of the California Institute of Technology in Pasadena, showed in the mid-1970s that when t = 2, for any k there is at most a finite number of exceptions—values of n that satisfy the divisibility rules but don’t have designs.

But for t greater than 2, no one knew whether designs should usually exist—and for values of tgreater than 5, they couldn’t even find a single example of a design. “There were people who felt strongly that [designs] would exist, and others who felt strongly that it’s too much to ask for,” Colbourn said.

In 1985, Vojtěch Rödl of Emory University in Atlanta offered mathematicians a consolation prize: He proved that it’s almost always possible to make a good approximate design—one that perhaps is missing a small fraction of the sets you want, but not many. Rödl’s approach uses a random process to gradually build up the collection of sets—a procedure that came to be known as the Rödl nibble, because, as Keevash put it, “instead of trying to swallow everything at once, you just take a nibble.”

Since then, the Rödl nibble has become a widely used tool in combinatorics, and has even been used in number theory. Last year, for example, mathematicians used it to help establish how far apart prime numbers can be.

But mathematicians agreed that the nibble wouldn’t be useful for attempts to make perfect designs. After all, at the end of Rödl’s procedure, you will typically have missed a small fraction of the smaller sets you need. To make a perfect design, you’d need to add in some additional larger groups that cover the missing sets. But unless you’re very lucky, those new larger groups are going to overlap with some of the groups that are already in your design, sending new errors cascading through your system.

Designs just didn’t seem to have the kind of flexibility that would allow a random approach to work. It seemed “obviously impossible,” Gowers said, that an approach like Rödl’s could be used to make perfect designs.

Last year, however—nearly three decades after Rödl’s work—Keevash showed that it is possible to control the cascade of errors by using an approach that marries flexibility and rigidity. Keevash modified Rödl’s construction by starting off the nibble with a specific collection of schoolgirl groups, called a “template,” that has particularly nice algebraic properties. At the end of the nibble, there will be errors to correct, but once the errors propagate into the template, Keevash showed, they can almost always be fixed there in a finite number of steps, producing a perfect design. “The full proof is extremely delicate and it is a phenomenal achievement,”wrote Ross Kang, of Radboud University in the Netherlands.

“I think a few years ago, nobody thought that a proof was on the horizon,” Colbourn said. “It’s an extraordinary breakthrough.”

For pure mathematicians, Keevash’s result is in a sense the end of the story: It establishes that for any parameters t and k, all values of n that fit the divisibility conditions will have a design, apart from at most a finite number of exceptions. “It sort of kills off a whole class of problems,” Gowers said.

But Keevash’s result leaves many mysteries unsolved for people who care about actual designs. In theory, his template-nibble approach could be used to create designs, but for now it’s unclear how large n has to be for his method to work, or how long an algorithm based on his method would take to run. And while Keevash has proved that designs almost always exist, his result doesn’t say whether a design will exist for any particular set of parameters you might care about. “People will presumably still work on this for generations,” Wilson said.

An illustration of the nine prisoners problem from Martin Gardner’s book The Last Recreations. Martin Gardner / Springer Science+Business Media

Still, Keevash’s result will shift the mindset of mathematicians who are trying to find designs, Colbourn said. “Before, it wasn’t clear whether the focus should be on constructing designs or proving they don’t exist,” he said. “Now at least we know the effort should focus on constructing them.”

And the shortage of information about specific designs leaves plenty of fun puzzles for recreational mathematicians to solve. So in the spirit of Kirkman, we will leave the gentle reader with another brainteaser, a slight variation on the schoolgirl puzzle devised in 1917 by the British puzzle aficionado Henry Ernest Dudeney and later popularized by Martin Gardner: Nine prisoners are taken outdoors for exercise in rows of three, with each adjacent pair of prisoners linked by handcuffs, on each of the six weekdays (back in Dudeney’s less enlightened times, Saturday was still a weekday). Can the prisoners be arranged over the course of the six days so that each pair of prisoners shares handcuffs exactly once?

Dudeney wrote that this puzzle is “quite a different problem from the old one of the Fifteen Schoolgirls, and it will be found to be a fascinating teaser and amply repay for the leisure time spent on its solution.” Happy solving!

Original story reprinted with permission fromQuanta Magazine, an editorially independent publication of the Simons Foundation whose mission is to enhance public understanding of science by covering research developments and trends in mathematics and the physical and life sciences.

Answer to a 150-Year-Old Math Conundrum Brings More Mystery

Saturday, June 20, 2015

In order to understand how the organ selectively transmits cells from mother to child

A placenta on a chip device

Courtesy of the Eunice Kennedy Shriver National Institute of Child Health and Human Development

From lungs to brains, organ tissues grown on a lab are telling researchers a lot about how their cells do their jobs. Now researchers are using the technology to better understand the placenta, the temporary organ that connects a fetus and mother during pregnancy.

The placenta’s primary function is to act as a “crossing guard” between mother and child—it sends the good stuff (like nutrients and oxygen) along to the baby, while leaving other damaging elements like chemicals from environmental exposure or disease-causing bacteria or viruses. If the placenta is damaged or doesn’t work right, it could endanger the health of both the mother and the baby.

Researchers don’t really know how the placenta is able to transmit the good things while keeping out the bad. That’s because the placenta is notoriously difficult to study in humans—it takes a long time, varies a lot between individual patients, and could put the fetus’ safety at risk. In the past, most studies about the placenta were done in animals to work around these issues. Animal studies have shed some light on how the placenta works, but the tissue is never quite the same as in humans.

A rendering of the placenta on a chip

Scientists Are Growing A Human Placenta On A Chip

Friday, June 19, 2015


The Apple Watch is barely two months old, but details are already starting to come out about what's planned for the next model. 9to5Macreports that Apple is currently planning to put a camera for video chatting on the top bezel of the Watch. It may also gain more independence from the iPhone by including a new wireless chip that would allow the Watch to use Wi-Fi to handle more advanced tasks. Apple is also said to be satisfied with the Watch's battery life and not focused on improving it for the next model. The report warns that Apple's current plans could be scrapped and saved for future models, depending on how development goes.

Video chatting sounds futuristic but frustrating

The addition of a video camera to the Watch is, arguably, a strange next step. While video chatting on a smartwatch certainly has a wonderfully futuristic vibe that could help to sell the new model, it could have significant downsides, including rapidly draining the Watch's battery, requiring an awkward arm position for an extended period of time, and only displaying the video on a very small screen. Of course, Apple also made the inclusion of front-facing smartphone cameras explode, so it's not worth counting this idea out based on the concept alone. Samsung has previously included a camera in a smartwatch, although it was oriented for taking photos.

Including more capable wireless abilities in the next Watch is certainly an important addition. The Watch is currently quite limited because it pretty much always needs to be paired to an iPhone over Bluetooth in order to work. It can currently do some functions over Wi-Fi, but it's largely meant as a backup — not as a way to use the Watch without a phone. It's not clear how much of that would change with an update to the Watch, but any alterations that let it grow a bit more independent are still meaningful and convenient steps forward.

Apple's customer research has apparently indicated that people are satisfied with the Watch's battery life, 9to5Mac reports. It's true that the Watch, typically, does make it through the day. But, much like the iPhone, if you actually decide to use the Watch in a significant way one day, there's a good chance that it'll run out quickly — and it's pretty rough having a dead Watch on your wrist. It's not entirely surprising then that Apple is trying to focus on new features while maintaining the Watch's existing battery life, but it would be nice to see improvement in that area in the future.

New high-end models could sit beneath the gold Editions

In addition to the new features, 9to5Mac reports that Apple is considering making a new high-end version of the Watch. It could be either an extension of the Apple Watch line or a new line that sits above the Apple Watch but well below the Edition. Apple reportedly wants to target people willing to spend more than $1,000, but not quite the $10,000 or so needed to buy a gold Edition. These new models could be the standard Apple Watch with new bands, or they could be part of a new line made with different materials, the report suggests.

There's been no real suggestion of when Apple will release the next version of the Watch, but it's likely that it won't be until next year. Apple typically updates its products on a one-year cycle, and the Watch is still only months old. It probably won't be ready for a refresh this fall, either, even when Apple releases watchOS 2, which brings with it support for native third-party apps. The updated software includes a number of other new features, including support for third-party complications, which could pretty quickly make the Watch a lot more useful.

Correction: This article previously stated that the Watch was incapable of updating apps like Weather over Wi-Fi. It can, so long as the network is already known through a paired iPhone.

The next Apple Watch could have a FaceTime camera

Researchers have built devices that harness changes in atmospheric humidity to generate small amounts of electricity, lift tiny weights, and even power a toy car. In the grand scheme of things, that captured energy is not free, but it’s pretty darn close. The study suggests that evaporation could be used to operate a variety of gadgets that don’t require a lot of power, scientists say.

“This is one of the first experiments to show that humidity can be a source of fuel,” says Albert Schenning, a materials scientist at the Eindhoven University of Technology in the Netherlands who wasn’t involved in the new study. The team’s designs, he says, “are very nice and very clever.”

All the gadgets rely on a simple phenomenon—the change in size of bacterial spores as they absorb moisture from the air and then release it, says team leader Ozgur Sahin, a biophysicist at Columbia University. Sahin and his colleagues used the living but dormant spores from Bacillus subtilis, a species of bacteria commonly found in soil and in the human gastrointestinal tract. Each spore typically swells and then shrinks up to 6% when moved from dry air to extremely humid air and then back again, Sahin says. The researchers harnessed that size-changing action by gluing thin layers of spores onto one side of curved sheets of polymer. When the spores swelled, that side of the polymer sheet lengthened—which in turn caused the curved sheet to somewhat straighten out. The stretching and contracting of these spore-coated polymer sheets are the driving force for the team’s devices.

A change in size of 6% may not sound that impressive. But when the researchers strung together a series of these polymer sheets, the “artificial muscles” they created quadrupled in length when relative humidity changed from below 30% to more than 80%, the team reports today in Nature Communications.  

The thicker the spore layer, the longer it would take for the muscles to react to changes in humidity. So, to make sure their artificial muscles were quick-acting, the researchers used spore layers that were extremely thin—no more than 3 micrometers thick, or about 5 spores deep on average, Sahin says. Tests showed that the devices could react to humidity changes within 3 seconds, he notes.

Tests also revealed that the spore-coated polymer strips could expand and shrink for more than 1 million cycles with little change in their range of motion. Other trials showed that the strips, when they shrank, could lift more than 50 times their own weight (video). But they did so much more slowly than an animal’s muscle would, so the power they generated—that is, their rate of energy production—was correspondingly low.

Nevertheless, the team harnessed changes in humidity to perform actual work. In one device, the back-and-forth motion driven by one artificial muscle suspended above a postage stamp–sized patch of water provided enough electrical power to light an LED. In another, the expansion of muscles on one side of a Ferris wheel–like device (where the air was humidified by evaporation from a wet paper towel) but not the other triggered an imbalance that caused the wheel to rotate (video). The team used the motion of a similar wheel to power a 100-gram toy car(video).

“These are fun demonstrations, but they prove the principle,” says Peter Fratzl, a materials scientist at the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany, who was not involved with the work. Researchers are constantly looking for sources of energy, even if they’re small, he notes. “It makes sense to use these gradients [in humidity], because they’re everywhere and they’re free.”

The team’s results are a good conceptual starting point, says George Whitesides, a chemist at Harvard University. Such devices could, in theory, generate enough electricity to run a few transistors, he adds. “But it will still be a while before these things are in every child’s bathtub.”

Energy harnessed from humidity can power small devices

After years of fasting, the Buddha’s “legs were like bamboo sticks, his backbone was like a rope, his chest was like an incomplete roof of a house, his eyes sank right inside, like stones in a deep well,” according to one account. The Buddha didn’t get what he wanted from this extreme fasting—enlightenment—but a new study suggests that a diet that replicates some effects of milder deprivation may not only lower your weight but also confer other benefits. Researchers report that following the diet for just 5 days a month improves several measures of health, including reducing the risk of developing cardiovascular disease.

Eating shortens life, and not just because overindulgence can lead to diseases such as diabetes. A diet that cuts food intake by up to 40%, known as calorie restriction, increases longevity in a variety of organisms and forestalls cancer, heart disease, and other late-life illnesses. Although some short-term studies suggest that calorie restriction provides metabolic benefits to people, nobody has confirmed that it also increases human life span. The closest researchers have come are two large, long-term studies of monkeys, and they conflict about whether meager rations increase longevity.

Even if calorie restriction could add years to our lives, almost no one can muster the willpower to eat so little day after day, year after year. An alternative that might be more, er, palatable is fasting, the temporary abstinence from food. Gerontological researcher Valter Longo of the University of Southern California in Los Angeles and colleagues have shown that fasting eases side effects of chemotherapy such as fatigue and weakness, and animal studies suggest that it produces health advantages similar to calorie restriction.

But hard-core fasting, in which people drink only water for days at a time, may be no easier than calorie restriction. “I’ve done it, and it was excruciating,” Longo says. For the new study he and his colleagues devised a less grueling diet that might still trigger the benefits of fasting. For two 4-day periods each month, middle-aged mice dined on low-protein, low-calorie chow. The rest of the month, they could nosh as much as they wanted.

The mice outlived their peers by an average of 3 months, a substantial amount for the rodents, and they displayed numerous signs of better health. As the researchers report online today inCell Metabolism, the mice shed fat and were 45% less likely to fall victim to cancer. During their lean cuisine episodes, their level of blood sugar fell by 40% and the amount of insulin in the blood was 90% lower. And although brainpower usually declines with age, the mice retained more of their mental ability; they bested control animals in two kinds of memory tests, perhaps because they produced more new neurons in the hippocampus, a brain area crucial for memory.

Longo and colleagues also uncovered evidence that the regimen boosted the animals’ capacity to restore and replenish their tissues. “That’s the most exciting” finding, Longo says. For instance, regeneration of the liver was quicker in the fasting animals, and the balance of different types of cells in their blood was more youthful. The numbers of certain stem cells also soared in the dieting rodents.

To determine whether occasional austerity might have the same impact on people, the researchers whipped up a menu of energy bars, soups, teas, and chips. One day’s fare furnishes between 725 and 1090 calories. “It’s not like eating ravioli, but it is better than going without,” Longo says. (The average adult man in America needs about 2000 to 3000 calories daily; people following calorie restriction may limit themselves to as few as 1200 calories.)

Much like the mice, the volunteers in the study followed the diet for 5 days straight and then returned to their usual dining habits for the rest of the month. In their paper, the researchers report the results for the first group of 19 subjects to try this “fasting mimicking” regimen and for 19 controls.

Only three rounds of alternating between the diet and normal eating appeared to improve the participants’ physical condition, reducing blood glucose, trimming abdominal fat, and cutting levels of a protein associated with a higher risk of cardiovascular disease. Longo and colleagues also detected a slight rise in the abundance of some stem cells in the blood, suggesting that the diet might promote regeneration in humans. “We think that what the fasting mimicking diet does is rejuvenate,” Longo says.

Other researchers say the results of the study are encouraging. “This single dietary change can counteract all these variables of aging, and I think that’s very impressive,” says molecular biologist Christopher Hine of the Harvard School of Public Health in Boston. The study shows that cutting calories all the time may not be necessary, adds biochemist James Mitchell, also of the Harvard School of Public Health. “Intermittent periods can have lasting effects.”

The new diet may also be more practical. “Calorie restriction has failed miserably in human trials” because it’s so hard to stick to, says gerontologist Rafael de Cabo of the U.S. National Institute on Aging in Baltimore, Maryland, who leads one of the monkey studies of calorie restriction. A regimen like the researchers use “is achievable,” he says.

Longo and colleagues have already completed a larger clinical trial of the diet with more than 80 subjects. Fasting like the Buddha is dangerous, and even the fasting mimicking diet could be harmful for some people, such as diabetics, Longo notes. Researchers need to study how the regimen works, who might benefit, and who might be harmed by it, Mitchell notes. “There is a lot of information to figure out.”

Short-term fasting may improve health

Thursday, June 18, 2015

Sharp has announced that it has begun mass production of its in-cell type touch displays for smartphones this month. This design technique promises thinner, lighter displays, which could reduce the thickness and weight of upcoming smartphones.

Typically, smartphone displays are constructed from two layers. One layer for the actual light emitting parts, such as the LCD, with a separate touch recognition layer placed on top to detect user inputs. Sharp’s in-cell display technology integrates the two parts into the same layer, with touch sensor circuitry and LCD drive circuitry sitting side by side in the LCD module.

An example (not to scale) of how in-cell saves on display thickness.

Integrating the two parts into the same layer means that Sharp’s displays will end up being slightly thinner than before, enabling manufacturers to produce smaller devices or use the additional space for extra hardware, such as larger battery capacities.

Sharp has been at the cutting edge of several recent developments in mobile displays. As well as consistently pushing the limits of pixel density with a range of small form factor 4K panel prototypes, the company has also been pushing the use of IGZO backplane technology, resulting in lower power consumption and a wider range of possible free-form design shapes and sizes.

However, the company recently cut 6,000 jobs as part of this year’s restructuring plans, necessitated by Sharps’ third annual net loss in four years and a large bank bailout to keep the company afloat. Sharp’s LCD business accounts for the majority of its sales, thanks to orders from Apple and a number of Chinese manufacturers, so the company has been reluctant to make changes to this part of its business. Sharp seems to be hoping that new technologies will help increase orders from customers.

The first batch of in-cell displays to leave Sharp’s production line are destined for future smartphones. However, the company is also in the process of developing medium-sized in-cell touch displays for use in tablets and notebook PCs, where a little less bulk and weight will no doubt be even more appreciated.

Sharp in-cell display promises thinner smartphones


In an attempt to reverse evolution, the team has already made significant strides in mutating chickens back to the very creatures from which they descended. If that wasn’t enough genetic splicing and dicing, Harvard scientists attempted a similar feat recently by inserting the genes of a woolly mammoth into elephants in order to recreate the extinct beasts. Whoa baby.

If the four major differences between dinosaurs and birds are their tails, arms, hands and mouths, Horner and team have already flipped certain genetic switches in chicken embryos to reverse-engineer a bird’s beak into a dinosaur-like snout.

“Actually, the wings and hands are not as difficult,” Horner said, adding that a ‘Chickensoraus’ -- as he calls the creation -- is well on its way to becoming reality. “The tail is the biggest project. But on the other hand, we have been able to do some things recently that have given us hope that it won't take too long."

Scientists Say They Can Recreate Living Dinosaurs Within the Next 5 Years


#GalaxyNote5 #iPhone6s – Galaxy Note 5 said to launch in August ahead of iPhone 6s : Samsung recently denied any plans to rush the Galaxy Note 5’s release, but rumors of an early launch just won’t die. A new report out of Asia claims the flagship phablet could arrive in late August to get a head start on Apple’s next iPhone.

Earlier rumors claimed the Galaxy Note 5 could launch as soon as July, but even an August release could give Samsung a decent advantage over the competition. The company typically unveils each new Galaxy Note phone at IFA, an annual tech show held in Berlin in September.

An early release would likely also mean a standalone event separate from the Berlin-based expo. It’s not unheard of, but it does break Samsung’s tradition.

The Galaxy Note 5 will apparently pack a massive 5.89-inch display with a 2K resolution. Rumors also point to a 4100mAh battery, a USB-C port, upgraded flash memory and an in-house Exynos 7422 processor. We’re expecting an upgraded design too, likely with plenty of glass and metal to match the Galaxy S6.

We’re still not really sure when the Galaxy Note 5 will arrive. We’d love to see the new phablet launch earlier than expected, though Samsung’s flat out denial does seem pretty definitive. Still, considering how persistent this rumor has turned out to be, we wouldn’t be too surprised if the device surfaced sooner rather than later.

Galaxy Note 5 said to launch in August ahead of iPhone 6s

#Amazon #Student – Are You a Student? Amazon Wants to Give You $10 – If you’re a student looking for a good last-minute Father’s Day gift for your dad, Amazon may have just given you the perfect solution: buy him a $50 gift card as a present, and get a $10 credit for yourself. The offer is available only to Amazon Student members, and all the details can be found below.

Spend $50 or More on Select Father’s Day Amazon Gift Cards, Get a $10 Promotional Credit for Yourself


Show Dad you care with this Amazon Student-exclusive offer: Buy a Father’s Day gift card and get a $10 promotional code to spend on yourself. Just purchase at least $50 in select Father’s Day Amazon.com Gift Cards (shown below) in a single order by June 21, 2015 and we’ll email you a $10 promotional code to spend at Amazon.com. Here’s how:

1. Add at least $50 in Father’s Day gift cards (shown below) to your cart

2. Click the yellow button below or enter “STUDENTFD” in the “Gift Cards and Promotional Codes” box at checkout to qualify.

3. After your purchase, you’ll receive an email within 2 days containing a code for a $10 promotional credit that can be applied to your Amazon account for items sold and shipped by Amazon.com. Credit expires on August 31, 2015

A perfect present for dads, grandpas, and uncles, Amazon.com Gift Cards can be sent via email, printed at home, or sent through the mail (with Free One-Day Shipping). Amazon.com Gift Cards are redeemable storewide for millions of items and never expire. Learn how to use your promotional code. Terms and conditions apply; learn more.

Important Notification: This offer is valid ONLYto Amazon Student members with a free trial or paid membership to Amazon Prime. Not an Amazon Student? Go here to learn about and sign up for the program.

Are You a Student? Amazon Wants to Give You $10

 
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